Your Appointment
Location/Directions
Sioux Falls Specialty Hospital is located at 910 East 20th Street, Sioux Falls, SD 57105.
Valet parking is available at the 20th Street entrance for your convenience.
For patients, family and friends needing overnight accomodations in Sioux Falls, The Center Inn is located adjacent to the Specialty Hospital. Call (605) 334-9002 or 800-456-0074 for reservations.
Click here for a printable map with driving directions.

Driving Directions
If traveling from the Northwest:
From I-90, take I-229 south to 10th Street, Exit 6. Turn right on 10th Street and drive west to Cliff Ave. Turn left on Cliff Ave and drive straight south. Turn Right on 20th Street. The Hospital is located on the right side of the street.
If traveling from the Southwest:
From I-29 North, take I-229 North, Exit 75. Take I-229 to Cliff Avenue and drive straight north. Turn left on 20th Street. The Hospital is located on the right side of the street.
If traveling from the Northeast:
From I-90, take I-229 South to 10th Street, Exit 6. Turn right on 10th Street and drive west to Cliff Avenue. Turn left on Cliff Avenue and drive south. Turn right on 20th Street. The Hospital is located on the right side of the street.
If traveling from the Southeast:
Take 26th Street west to Cliff Avenue. Turn right on Cliff Avenue and drive north. Turn left on 20th Street. The Hospital is located on the right side of the street.
